Impact of 10 years of diethylcarbamazine and ivermectin mass administration on infection and transmission of lymphatic filariasis.
Identifieur interne : 007240 ( Main/Exploration ); précédent : 007239; suivant : 007241Impact of 10 years of diethylcarbamazine and ivermectin mass administration on infection and transmission of lymphatic filariasis.
Auteurs : K D Ramaiah [Inde] ; P K Das ; P. Vanamail ; S P PaniSource :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2007.
Descripteurs français
- KwdFr :
- Animaux, Calendrier d'administration des médicaments, Diéthylcarbamazine (administration et posologie), Diéthylcarbamazine (usage thérapeutique), Enfant, Enfant d'âge préscolaire, Femelle, Filaricides (administration et posologie), Filaricides (usage thérapeutique), Filariose lymphatique (), Filariose lymphatique (transmission), Filariose lymphatique (épidémiologie), Humains, Inde (épidémiologie), Ivermectine (administration et posologie), Ivermectine (usage thérapeutique), Mâle, Méthode en double aveugle, Nourrisson, Services de médecine préventive (), Wuchereria bancrofti ().
- MESH :
- administration et posologie : Diéthylcarbamazine, Filaricides, Ivermectine.
- usage thérapeutique : Diéthylcarbamazine, Filaricides, Filariose lymphatique, Ivermectine.
- épidémiologie : Filariose lymphatique, Inde.
- Animaux, Calendrier d'administration des médicaments, Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique, Humains, Mâle, Méthode en double aveugle, Nourrisson, Services de médecine préventive, Wuchereria bancrofti.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- Animals, Child, Child, Preschool, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (therapeutic use), Double-Blind Method, Drug Administration Schedule, Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (prevention & control), Elephantiasis, Filarial (transmission), Female, Filaricides (administration & dosage), Filaricides (therapeutic use), Humans, India (epidemiology), Infant, Ivermectin (administration & dosage), Ivermectin (therapeutic use), Male, Preventive Health Services (methods), Wuchereria bancrofti (drug effects).
- MESH :
- chemical , administration & dosage : Diethylcarbamazine, Filaricides, Ivermectin.
- chemical , therapeutic use : Diethylcarbamazine, Filaricides, Ivermectin.
- geographic , epidemiology : India.
- drug effects : Wuchereria bancrofti.
- epidemiology : Elephantiasis, Filarial.
- methods : Preventive Health Services.
- prevention & control : Elephantiasis, Filarial.
- transmission : Elephantiasis, Filarial.
- Animals, Child, Child, Preschool, Double-Blind Method, Drug Administration Schedule, Female, Humans, Infant, Male.
Abstract
The potential of repeated mass administration of diethylcarbamazine (DEC) and ivermectin to eliminate lymphatic filariasis has been examined in a study implemented in 10 villages with a population of 18415 in south India. During ten rounds of mass drug administration, 49-84% of the eligible population received treatment in different villages. Ten rounds of mass administration of DEC alone reduced the microfilaria (mf) prevalence and intensity by 93% and 97%, respectively, and the vector infection and infectivity rates by 91% and 89%, respectively. The corresponding figures with nine rounds of administration of ivermectin alone were 83%, 90%, 89% and 79%. Out of five villages in each treatment arm, the mf rate declined to
DOI: 10.1016/j.trstmh.2006.12.004
PubMed: 17374389
DOI: 10.1016/j.trstmh.2006.12.004
PubMed: 17374389
Affiliations:
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Vanamail</name></author><author><name sortKey="Pani, S P" sort="Pani, S P" uniqKey="Pani S" first="S P" last="Pani">S P Pani</name></author></analytic><series><title level="j">Transactions of the Royal Society of Tropical Medicine and Hygiene</title><idno type="ISSN">0035-9203</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Child</term><term>Child, Preschool</term><term>Diethylcarbamazine (administration & dosage)</term><term>Diethylcarbamazine (therapeutic use)</term><term>Double-Blind Method</term><term>Drug Administration Schedule</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (prevention & control)</term><term>Elephantiasis, Filarial (transmission)</term><term>Female</term><term>Filaricides (administration & dosage)</term><term>Filaricides (therapeutic use)</term><term>Humans</term><term>India (epidemiology)</term><term>Infant</term><term>Ivermectin (administration & dosage)</term><term>Ivermectin (therapeutic use)</term><term>Male</term><term>Preventive Health Services (methods)</term><term>Wuchereria bancrofti (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Calendrier d'administration des médicaments</term><term>Diéthylcarbamazine (administration et posologie)</term><term>Diéthylcarbamazine (usage thérapeutique)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Filaricides (administration et posologie)</term><term>Filaricides (usage thérapeutique)</term><term>Filariose lymphatique ()</term><term>Filariose lymphatique (transmission)</term><term>Filariose lymphatique (épidémiologie)</term><term>Humains</term><term>Inde (épidémiologie)</term><term>Ivermectine (administration et posologie)</term><term>Ivermectine (usage thérapeutique)</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nourrisson</term><term>Services de médecine préventive ()</term><term>Wuchereria bancrofti ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term><term>Ivermectin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term><term>Ivermectin</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>India</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Ivermectine</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Preventive Health Services</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Filariose lymphatique</term><term>Ivermectine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Inde</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Child</term><term>Child, Preschool</term><term>Double-Blind Method</term><term>Drug Administration Schedule</term><term>Female</term><term>Humans</term><term>Infant</term><term>Male</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Calendrier d'administration des médicaments</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Filariose lymphatique</term><term>Humains</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nourrisson</term><term>Services de médecine préventive</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Inde</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The potential of repeated mass administration of diethylcarbamazine (DEC) and ivermectin to eliminate lymphatic filariasis has been examined in a study implemented in 10 villages with a population of 18415 in south India. During ten rounds of mass drug administration, 49-84% of the eligible population received treatment in different villages. Ten rounds of mass administration of DEC alone reduced the microfilaria (mf) prevalence and intensity by 93% and 97%, respectively, and the vector infection and infectivity rates by 91% and 89%, respectively. The corresponding figures with nine rounds of administration of ivermectin alone were 83%, 90%, 89% and 79%. Out of five villages in each treatment arm, the mf rate declined to </div> </front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Das, P K" sort="Das, P K" uniqKey="Das P" first="P K" last="Das">P K Das</name><name sortKey="Pani, S P" sort="Pani, S P" uniqKey="Pani S" first="S P" last="Pani">S P Pani</name><name sortKey="Vanamail, P" sort="Vanamail, P" uniqKey="Vanamail P" first="P" last="Vanamail">P. Vanamail</name></noCountry><country name="Inde"><noRegion><name sortKey="Ramaiah, K D" sort="Ramaiah, K D" uniqKey="Ramaiah K" first="K D" last="Ramaiah">K D Ramaiah</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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